The Short Version
Multiple peer-reviewed, nationally representative studies published in 2025 — including Ethiopia's Third National TB Drug Resistance Survey — quantify isoniazid mono-resistant TB prevalence at approximately 4.1% among new cases. These constitute documented, measurable prevalence data that remain the authoritative reference as of April 2026, with no contradicting evidence suggesting elimination or significant change. Variation across studies (0.9%–6.23%) reflects differences in study populations and methods, not an absence of measurement.