Friday, Jul 24, 2026 The claims desk. Receipts included. POWERED BY LENZ ↗
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HEALTH

The Claim

A prospective Fudan University study of 724 patients with recent myocardial infarction found that soluble interleukin-2 receptor (sIL-2R) was an independent predictor of long-term major adverse cardiac events, reporting an unadjusted hazard ratio of 9.123 (95% CI 5.883–14.147) and an adjusted hazard ratio of 3.761 (95% CI 2.269–6.233) with p < 0.001.

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The Short Version

The cited study details are supported by the published record. Multiple authoritative versions of the same Fudan/Zhongshan cohort paper report 724 patients, a prospective design, and the exact unadjusted and adjusted hazard ratios with p<0.001. The main caveat is a likely misindexed older database entry, plus the study’s single-center design and cutoff-based analysis.

Caveats

  • The hazard ratios come from a single-center Fudan/Zhongshan cohort, so generalizability to other populations may be limited.
  • The reported effect sizes are based on high-versus-low sIL-2R groups defined by a cutoff, not necessarily a per-unit increase in the biomarker.
  • One database record appears misdated or misindexed; it raises attribution confusion but does not negate the published study findings.

The Receipts

  1. Prediction of long-term major adverse cardiac events after myocardial infarction based on sIL-2R and IL-8 in patients admitted to Zhongshan Hospital, Fudan University

    PubMed Central

  2. Prognostic value of soluble interleukin-2 receptor in patients with acute myocardial infarction

    PubMed

  3. Soluble interleukin-2 receptor combined with interleukin-8 is a powerful predictor of future adverse cardiovascular events in patients with acute myocardial infarction

    PubMed

  4. Soluble interleukin-2 receptor combined with interleukin-8 is a powerful predictor of future adverse cardiovascular events in patients with acute myocardial infarction

    PubMed Central

  5. Prediction of long-term major adverse cardiac events after myocardial infarction using soluble interleukin-2 receptor and interleukin-8

    Frontiers in Cardiovascular Medicine

  6. Prediction of long-term major adverse cardiac events after myocardial infarction using soluble interleukin-2 receptor and interleukin-8

    PubMed

  7. Soluble interleukin-2 receptor combined with interleukin-8 is a powerful predictor of future adverse cardiovascular events in patients with myocardial infarction

    Frontiers in Cardiovascular Medicine

  8. Soluble interleukin-2 receptor predicts acute kidney injury and in-hospital all-cause mortality in patients with acute myocardial infarction

    PubMed

  9. Association of soluble interleukin‐2 receptor α and tumour necrosis factor receptor 1 with incident heart failure in the multi‐ethnic study of atherosclerosis

    PubMed Central

  10. Supplementary tables – Soluble interleukin-2 receptor combined with interleukin-8 is associated with major adverse cardiovascular events in patients with myocardial infarction

    PubMed Central

+ 5 more sources — see the full list on Lenz

Filed Under

Fudan UniversityMajor Adverse Cardiac EventsMyocardial InfarctionSoluble Interleukin-2 Receptor

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