The Short Version
Current evidence does not support the definitive claim that vaping causes cancer in humans. Human studies showing elevated cancer risk involve dual users who also smoke combustible cigarettes — a known carcinogen — making it impossible to isolate vaping as the independent cause. Multiple systematic reviews find no significant cancer risk in exclusive never-smoker vapers. While biomarker evidence of DNA damage and a recent review calling vaping "likely" carcinogenic suggest biological plausibility, no authoritative body has confirmed a definitive causal link for vaping alone.