The Short Version
The claim contains a kernel of truth — sanctions often fail to reverse core security policies of hardened adversaries like Russia — but its sweeping "largely ineffective" framing is misleading. Aggregate studies show sanctions succeed in roughly 34–51% of cases involving modest policy demands, and the 2015 Iran nuclear deal is a prominent counterexample. Effectiveness varies significantly by objective, target, and design. Calling sanctions "largely ineffective" erases this meaningful variation and overstates the failure rate.